Dermatofibrosarcoma Protuberans

Rare type of cancerous sarcoma that arises from the dermis of the skin.

Screen Shot 2022 08 19 At 11.26.50 AM

What is a Dermatofibrosarcoma Protuberans?

Rare type of cancerous skin sarcoma that arises from the dermis of the skin. There is a good prognosis. The 10 year survival rate is 99.1%.

Who is usually affected?
Who is usually affected?
  • • Affects patients between 20 to 50 years old. 
Common Bones Involved
Common Bones Involved
  • • Most common location is around the torso (50%). 
  • • Associated with a genetic mutation called a t(17,22) chromosomal translocation. It is a somatic mutation so it does not run in families. 


Signs and Symptoms
Signs and Symptoms
  • • Grows slowly and starts as a flatness in the skin. Usually 1 to 5 cm in diameter. 
  • • Commonly seen as a reddish or purplish patch of skin.
  • • Might look like a pimple or feel like a rough patch of skin.
Biological Behavior
Biological Behavior
  • • Rare type of cancerous skin sarcoma.
  • • Arises from the dermis of the skin.
  • • Although a skin tumor, the disease tends to grow into surrounding fat and muscle.
  • • Slow-growing and rarely spreads, or metastasizes.


  • • The work-up often consists of a physical examination, X-rays, CT scans, MRI, and sometimes bone scans are required.
  • • MRI is the best imaging because it is the most sensitive. 
  • • The diagnosis is often confirmed with a biopsy, which means taking a sample of tumor and having it analyzed under a microscope by a pathologist. 

Risk to your limbs

Dermatofibrosarcoma Protuberans is a cancerous aggressive tumor that, if left unchecked, will grow and destroy your normal bone. As the tumor slowly grows, the bone is weakened and you are at an increased risk of breaking the bone due to the tumor (called a pathological fracture). They may also spread to your lungs or other bones.

Radiographic imaging is used to help form a diagnosis. These include X-Ray, MRI, CT and Bone Scans

An example of a MRI is shown.

Treatment of Dermatofibrosarcoma  Protuberans


I've seen many doctors and I can confidently attest Dr. Wittig is the preeminent orthopaedic specialist. He is genuinely kind and caring, as he demonstrated by completely addressing my concerns and compassionately relating to what I was dealing with. He clearly outlined the plan of attack, and recommended the two additional doctors who would become part of my 'team'. Dr. Wittig was so effective in allaying our fears and bringing us optimism. My surgery was significant, but I was up and walking the next day and back at the gym 5 weeks later. This is further testament to Dr. Wittig's skill. He saved my leg and my life, and I feel so very blessed to say he is my doctor. I have already recommended him to others, and I will continue to do so. I would trust him with my closest family and lifelong friends. BEST DOCTOR EVER.



Hey! I am Dr. Wittig.

Myself and my amazing team are dedicated to saving your life and your limb. Losing a limb because of a tumor can be a terrifying experience. But, it does not have to be the only option. I’ve spent 20+ years as a Board-Certified Orthopedic Surgeon and Orthopedic Oncologist.

I’ve devoted my career to helping children and adults afflicted with bone and soft tissue masses by performing complex limb saving surgeries. Most patients can have their limb saved, which may require innovative techniques.

Patients afflicted with musculoskeletal tumors have complex conditions that are best taken care of at large hospitals. I am the Chairman of Orthopedics and Chief of Orthopedic Oncology at Morristown Medical Center. My philosophy is a multidisciplinary team approach, working together to tailor treatment to individual patients. Education and research are essential to my practice, providing the best setting for extraordinary patient care. Because of this, we have some of the top results in the country.